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Znosko Lab CoSSMos Database

Welcome to the Znosko Lab RNA Characterization of Secondary Structure Motifs (RNA CoSSMos) database! This tool allows the systematic searching of all catalogued three-dimensional nucleic acid PDB structures that contain secondary structure motifs such as mismatches, (a)symmetric internal loops, hairpin loops, and bulge loops.

To utilize the search function of the database, please select "Search" at the top menu.

If you have any questions, please check out our Wiki here or e-mail us via the Contact Us page. Also, please consider registering with the CoSSMos database if this is your first visit.

This site functions best at resolutions of at least 1440x900 and is fully compatible with these and later versioned browsers: Internet Explorer 8, Firefox 3.6, Safari XX, and Google Chrome.

Lastly, users of the RNA CoSSMos database should cite:

Vanegas, P. L., Hudson, G. A., Davis, A. R., Kelly, S. C., Kirkpatrick, C. C., and Znosko, B. M. (2012) RNA CoSSMos: Characterization of Secondary Structure Motifs- a searchable database of secondary structure motifs in RNA three-dimensional structures, Nucleic Acids Res. 40, D439-D444.

and are encouraged to cite:

Gendron, P., Lemieux, S., and Major, F. (2001) Quantitative analysis of nucleic acid three-dimensional structures., J. Mol. Biol. 308, 919-936.

Lemieux, S., and Major, F. (2002) RNA canonical and non-canonical base pairing types: a recognition method and complete repertoire., Nucleic Acids Res. 30, 4250-4263.

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